Health-related quality of life in 153 children with neuromuscular disorders in Latin America: is it age, functional dependence or diagnosis?

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2024-09
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W.B. Saunders Ltd
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Neuromuscular diseases impact on children's health related quality of life but there is a lack of studies in Latin America that measured this construct. To respond to this need, this study aimed to explore quality of life and its relationship with age, functional dependence and specific diagnosis in children and adolescents in Latin America. A cross-sectional correlation study was carried out with 133 caregivers on children (2–18 years old) with various neuromuscular disorders. Parents reported on their children's health related quality of life through the PedsQL GCS and the PedsQL NMM. Differences in quality of life were found when comparing children with high functional dependence with those with mild dependence (p = 0.05). No significant differences were found regarding the child diagnosis. Finally, quality of life was highly correlated with the child's age, even when controlling for functional dependence differences between ages. Children and adolescents with neuromuscular show a diminished health related quality of life, not only in physical functioning but in their psychosocial functioning. Health related quality of life may vary according to the child's age and functional dependence.
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Ortega, J., Vázquez, N., Amayra Caro, I., Muntadas, J., Squitín Tasende, M., & Rodriguez Bermejo, A. (2024). Health-related quality of life in 153 children with neuromuscular disorders in Latin America: is it age, functional dependence or diagnosis? European Journal of Paediatric Neurology, 52, 95-102. https://doi.org/10.1016/J.EJPN.2024.08.007
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