Repositorio Institucional
El repositorio institucional recoge la producción científica del personal docente e investigador de la Universidad de Deusto. Su propósito es reunir, archivar, preservar y aumentar la visibilidad en acceso abierto de los resultados de investigación.
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La transformación de las relaciones comerciales en las agencias de viajes
(Servizo de Publicacións, Universidade da Coruña, 2021-02-01) Pastor Ruiz, Ricardo; Fernández-Villarán Ara, Asunción
Las agencias de viajes tradicionales han sido el canal de distribución principal en la intermediación turística. Un área estática durante años, que se ha modificado radicalmente debido al aumento del uso de internet y la revolución móvil, y que ha evolucionado hacia una reintermediación o hipermediación. Se puede afirmar que vivimos en un nuevo escenario de la intermediación turística y que sigue evolucionando y cambiando de manera muy rápida, aunque manteniendo los actores principales. Este trabajo se centra en las estrategias y modelos de actuación de las agencias de viajes minoristas físicas en España ante el nuevo escenario. Por medio de diferentes encuestas y entrevistas a proveedores y agentes de viajes, se analizan las relaciones entre ambos, así como los nuevos hábitos de comportamiento entre las dos partes de un sector en el que, hasta ahora, participaban de manera absolutamente coordinada en todas las acciones que se proponían.
Implementing exercise in standard cancer care (bizi orain hybrid exercise program): protocol for a randomized controlled trial
(JMIR Publications Inc., 2021-08-01) Arietaleanizbeaskoa, María Soledad; Gil Rey, Erreka
; Mendizabal Gallastegui, Nere
; García Álvarez, Arturo
; de la Fuente, Ibon; Domínguez Martínez, Silvia; Pablo, Susana; Coca Núñez, Aitor; Gutiérrez Santamaría, Borja; Grandes Odriozola, Gonzalo
Background: Despite the established benefits of regular exercise for patients with cancer to counteract the deleterious effects of the disease itself and treatment-related adverse effects, most of them do not engage in sufficient levels of physical activity and there is a paucity of data on the integration of efficacious exercise programs that are accessible and generalizable to a large proportion of patients with cancer into routine cancer care. Objective: We intend to examine the effects attributable to the implementation of a community-based exercise program on cardiorespiratory functional capacity and quality of life for patients with cancer. Methods: This will be a hybrid study. In the first experimental phase, patients diagnosed with any type of cancer will be randomized into two parallel groups. One group immediately performs Bizi Orain, a 3-month supervised exercise program (3 times a week), in addition to behavioral counseling in a primary health care setting; the other is a reference group that starts the exercise program 3 months later (delayed treatment). In the second observational phase, the entire cohort of participants will be followed-up for 5 years. Any person diagnosed with cancer in the previous 2 years is eligible for the program. The program evaluation involves the uptake, safety, adherence, and effectiveness assessed after completion of the program and with follow-ups at 3, 6, 12, 24, 36, 48, and 60 months. The primary outcomes of the experimental study, to be compared between groups, are improved physical function and quality of life, whereas overall survival is the main objective of the prospective study. To analyze the association between changes in physical activity levels and overall survival, longitudinal mixed-effects models will be used for repeated follow-up measures. Results: A total of 265 patients have been enrolled into the study since January 2019, with 42 patients from the hematology service and 223 from the oncology service. Conclusions: Bizi Orain is the first population-based exercise program in Spain that will offer more insight into the implementation of feasible, generalizable, and sustainable supportive care services involving structured exercise to extend survival of patients with cancer, improve their physical function and quality of life, and reverse the adverse effects of their disease and related treatments, thereby reducing the clinical burden. Trial Registration: ClinicalTrials.gov NCT03819595; http://clinicaltrials.gov/ct2/show/NCT03819595 International Registered Report Identifier (IRRID): DERR1-10.2196/24835.
COVID-19 in gastroenterology: where are we now?: current evidence on the impact of COVID-19 in gastroenterology
(John Wiley and Sons Inc, 2021-06-30) Magro, Fernando; Nuzzo, Alexandre; Abreu, Cândida; Libânio, Diogo; Rodríguez Lago, Iago
; Pawlak, Katarzyna; Hollenbach, Marcus; Brouwer, Willem P.; Siau, Keng
Background: The COVID-19 pandemic has created unprecedented challenges in all fields of society with social, economic, and health-related consequences worldwide. In this context, gastroenterology patients and healthcare systems and professionals have seen their routines changed and were forced to adapt, adopting measures to minimize the risk of infection while guaranteeing continuous medical care to chronic patients. Objective: At this point, it is important to evaluate the impact of the pandemic on this field to further improve the quality of the services provided in this context. Methods/Results/Conclusion: We performed a literature review that summarizes the main aspects to consider in gastroenterology, during the pandemic crisis, and includes a deep discussion on the main changes affecting gastroenterology patients and healthcare systems, anticipating the pandemic recovery scenario with future practices and policies.
Biofeedback applied to interactive serious games to monitor frailty in an elderly population
(MDPI AG, 2021-04-14) Shapoval, Serhii
; García-Zapirain, Begoña
; Méndez Zorrilla, Amaia; Mugueta Aguinaga, Iranzu
This article proposes an example of a multiplatform interactive serious game, which is an additional tool and assistant used in the rehabilitation of patients with musculoskeletal system problems. In medicine, any actions and procedures aimed at helping the rehabilitation of patients should entail the most comfortable, but at the same time, effective approach. Regardless of how these actions are orientated, whether for rehabilitation following surgery, fractures, any problems with the musculoskeletal system, or just support for the elderly, rehabilitation methods undoubtedly have good goals, although often the process itself can cause all kinds of discomfort and aversion among patients. This paper presents an interactive platform which enables a slightly different approach to be applied in terms of routine rehabilitation activities and this will help make the process more exciting. The main feature of the system is that it works in several ways: for normal everyday use at home, or for more in-depth observation of various biological parameters, such as heart rate, temperature, and so on. The basic component of the system is the real-time tracking system of the body position, which constitutes both a way to control the game (controller) and a means to analyze the player’s activity. As for the closer control of rehabilitation, the platform also provides the opportunity for medical personnel to monitor the player in real time, with all the data obtained from the game being used for subsequent analysis and comparison. Following several laboratory tests and feedback analysis, the progress indicators are quite encouraging in terms of greater patient interest in this kind of interaction, and effectiveness of the developed platform is also on average about 30–50% compared to conventional exercises, which makes it more attractive in terms of patient support.
Contributions of sex, depression, and cognition on brain connectivity dynamics in Parkinson’s disease
(Nature Research, 2021-12-16) Díez Cirarda, María
; Gabilondo Cuellar, Iñigo; Ibarretxe Bilbao, Naroa; Gómez Esteban, Juan Carlos; Kim, Jinhee; Lucas Jiménez, Olaia; Pino, Rocío del; Peña Lasa, Javier
; Ojeda del Pozo, Natalia
; Mihaescu, Alexander; Valli, Mikaeel; Acera Gil, María Ángeles
; Cabrera Zubizarreta, Alberto
; Gómez Beldarrain, María Ángeles
; Strafella, Antonio P.
Alterations in time-varying functional connectivity (FC) have been found in Parkinson’s disease (PD) patients. To date, very little is known about the influence of sex on brain FC in PD patients and how this could be related to disease severity. The first objective was to evaluate the influence of sex on dynamic FC characteristics in PD patients and healthy controls (HC), while the second aim was to investigate the temporal patterns of dynamic connectivity related to PD motor and non-motor symptoms. Ninety-nine PD patients and sixty-two HC underwent a neuropsychological and clinical assessment. Rs-fMRI and T1-weighted MRI were also acquired. Dynamic FC analyses were performed in the GIFT toolbox. Dynamic FC analyses identified two States: State I, characterized by within-network positive coupling; and State II that showed between-network connectivity, mostly involving somatomotor and visual networks. Sex differences were found in dynamic indexes in HC but these differences were not observed in PD. Hierarchical clustering analysis identified three phenotypically distinct PD subgroups: (1) Subgroup A was characterized by mild motor symptoms; (2) Subgroup B was characterized by depressive and motor symptoms; (3) Subgroup C was characterized by cognitive and motor symptoms. Results revealed that changes in the temporal properties of connectivity were related to the motor/non-motor outcomes of PD severity. Findings suggest that while in HC sex differences may play a certain role in dynamic connectivity patterns, in PD patients, these effects may be overcome by the neurodegenerative process. Changes in the temporal properties of connectivity in PD were mainly related to the clinical markers of PD severity.