Cognitive, creative, functional, and clinical symptom improvements in schizophrenia after an integrative cognitive remediation program: a randomized controlled trial

Vista sencilla de ítem
dc.contributor.authorSampedro, Agurne
dc.contributor.authorPeña Lasa, Javier
dc.contributor.authorSánchez Gómez, Pedro Manuel
dc.contributor.authorIbarretxe Bilbao, Naroa
dc.contributor.authorGómez Gastiasoro, Ainara
dc.contributor.authorIriarte Yoller, Nagore
dc.contributor.authorPavón, Cristóbal
dc.contributor.authorTous Espelosín, Mikel
dc.contributor.authorOjeda del Pozo, Natalia
dc.date.accessioned2024-11-14T14:54:52Z
dc.date.available2024-11-14T14:54:52Z
dc.date.issued2021-12
dc.date.updated2024-11-14T14:54:52Z
dc.description.abstractThis study analyzed the effectiveness of an integrative cognitive remediation program (REHACOP) in improving neurocognition, social cognition, creativity, functional outcome, and clinical symptoms in patients with schizophrenia. In addition, possible mediators predicting improvement in functional outcomes were explored. The program combined cognitive remediation with social cognitive training and social and functional skill training over 20 weeks. The sample included 94 patients, 47 in the REHACOP group and 47 in the active control group (occupational activities). Significant differences were found between the two groups in change scores of processing speed, working memory, verbal memory (VM), inhibition, theory of mind, emotion processing (EP), figural creative strengths, functional competence, disorganization, excitement, and primary negative symptoms. A mediational analysis revealed that changes in VM, inhibition, and EP partially explained the effect of cognitive remediation on functional competence improvement. This study provides initial evidence of the effect of integrative cognitive remediation on primary negative symptoms and creativity.en
dc.description.sponsorshipThis work was supported by the Carlos III Health Institute of the Spanish Ministry of Economy and Competitiveness (PI16/01022); the Department of Education and Science of the Basque Government (Team A) (IT946‐16); the Fundación Tatiana Pérez de Guzmán el Bueno (to AS); and the University of the Basque Country (UPV/EHU) (PIF 19/40 to MTE).en
dc.identifier.citationSampedro, A., Peña, J., Sánchez, P., Ibarretxe-Bilbao, N., Gómez-Gastiasoro, A., Iriarte-Yoller, N., Pavón, C., Tous-Espelosin, M., & Ojeda, N. (2021). Cognitive, creative, functional, and clinical symptom improvements in schizophrenia after an integrative cognitive remediation program: a randomized controlled trial. npj Schizophrenia, 7(1). https://doi.org/10.1038/S41537-021-00181-0
dc.identifier.doi10.1038/S41537-021-00181-0
dc.identifier.urihttp://hdl.handle.net/20.500.14454/1876
dc.language.isoeng
dc.publisherNature Research
dc.rights© The Author(s) 2021
dc.titleCognitive, creative, functional, and clinical symptom improvements in schizophrenia after an integrative cognitive remediation program: a randomized controlled trialen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.issue1
oaire.citation.titlenpj Schizophrenia
oaire.citation.volume7
oaire.licenseConditionhttps://creativecommons.org/licenses/by/4.0/
oaire.versionVoR
Ficheros en el ítem
Bloque original
Mostrando 1 - 1 de 1
Miniatura
Nombre:
sampedro_cognitive_2021.pdf
Tamaño:
1.04 MB
Formato:
Adobe Portable Document Format
Descargar
Colecciones
Artículos