As we were and as we should be, combined exercise training in adults with schizophrenia: CORTEX-SP study part II

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dc.contributor.authorTous Espelosín, Mikel
dc.contributor.authorPavón, Cristóbal
dc.contributor.authorElizagarate Zabala, Edorta
dc.contributor.authorSampedro, Agurne
dc.contributor.authorMaldonado-Martín, Sara
dc.date.accessioned2025-03-10T10:30:33Z
dc.date.available2025-03-10T10:30:33Z
dc.date.issued2024-08
dc.date.updated2025-03-10T10:30:33Z
dc.description.abstractObjective: To determine the changes in health-related quality of life (HRQoL) and sleep quality following a supervised combined exercise (EX) program compared to a Treatment-As-Usual (TAU) and to analyze the relationship between the differences in cardiorespiratory fitness (CRF) and HRQoL domains in people with schizophrenia (SZ). Methods: The SZ (n = 112, 41.3 ± 10.4 year) was randomly assigned into a TAU control group (n = 53) or EX-group (n = 59, 3 days/week). The 36-item Short-Form Health Survey questionnaire assessed HRQoL and the sleep quality analysis (accelerometry). Results: After the intervention (20 weeks), physical functioning (∆ = 12.9%), general health (∆ = 15.3%), mental health (∆ = 8.3%), physical component summary (PCS) (∆ = 5.1%), and sleep efficiency (∆ = 1.9%) increased (p < 0.05) in the EX, with no significant changes in the TAU for any domains studied. There were significant differences between groups whose EX showed improvements (p < 0.05) compared to TAU in physical functioning, general health, PCS, and sleep efficiency. A greater CRF was associated with better values in physical functioning, role-physical, bodily pain, general health, vitality, and PCS after the exercise program in SZ. Conclusions: A 20-week supervised combined exercise intervention program for SZ increased sleep efficiency and physical functioning, general and mental health, and PCS scores. This could lead to a critical HRQoL change from how they were to how they should be. Trial Registration: ClinicalTrials.gov identifier: NCT03509597.en
dc.description.sponsorshipThis study was supported by the Spanish Ministry of Economy and Competitiveness, “Fondo de Investigación Sanitaria del Instituto de Salud Carlos III” (PI16/01022). The University of the Basque Country (UPV/EHU, PIF19/40) with a predoctoral grant supported MTE. The Council of Vitoria-Gasteiz provides the facilities of the Physical Activity and Health Research Centre for exercise interventionen
dc.identifier.citationTous-Espelosin, M., Pavon, C., Elizagarate, E., Sampedro, A., & Maldonado-Martín, S. (2024). As We Were and As We Should Be, Combined Exercise Training in Adults With Schizophrenia: CORTEX-SP Study Part II. Scandinavian Journal of Medicine and Science in Sports, 34(8). https://doi.org/10.1111/SMS.14707
dc.identifier.doi10.1111/SMS.14707
dc.identifier.eissn1600-0838
dc.identifier.issn0905-7188
dc.identifier.urihttp://hdl.handle.net/20.500.14454/2499
dc.language.isoeng
dc.publisherJohn Wiley and Sons Inc
dc.rights© 2024 The Author(s)
dc.subject.otherCombined training
dc.subject.otherMental health
dc.subject.otherPhysical health
dc.subject.otherSF-36 questionnaire
dc.subject.otherSleep quality
dc.titleAs we were and as we should be, combined exercise training in adults with schizophrenia: CORTEX-SP study part IIen
dc.typejournal article
dcterms.accessRightsopen access
oaire.citation.issue8
oaire.citation.titleScandinavian Journal of Medicine and Science in Sports
oaire.citation.volume34
oaire.licenseConditionhttps://creativecommons.org/licenses/by-nc-nd/4.0/
oaire.versionVoR
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